Metformin: Environmental fate and effects study

This study will determine the toxic effect the pharmaceutical metformin has on an aquatic environment. Chronic exposures were conducted at Lake 114 located at the International Institute for Sustainable Development-Experimental Lakes Area (IILSD-ELA) in Ontario, Canada. Three concentrations of metformin were used to study the effects on the adult and embryo life stages of the fathead minnow (Pimephales promelas) as well as the effect on the food chain within the mesocosms. Water samples for basic chemistry and nutrient samples were collected throughout the exposures. There is currently one publication and the authors plan to submit two more manuscripts from this research project. All data are a part subject of a publication containing method details, full QA/QC, interpretations and conclusions. Citation: Nielsen, K. M., DeCamp, L., Birgisson, M., Palace, V. P., Kidd, K. A., Parrott, J. L., McMaster, M. E., Alaee, M., Blandford, N., & Ussery, E. J. (2022). Comparative Effects of Embryonic Metformin Exposure on Wild and Laboratory-Spawned Fathead Minnow (Pimephales promelas) Populations. Environmental science & technology, 56(14), 10193–10203. doi.org/10.1021/acs.est.2c01079…

Publisher

Environment and Climate Change Canada

Resources

2

Catalogue metadata updated

2023-12-17