Scientific Publication - Toxicity of sediment-associated substituted phenylamine antioxidants on the early life stages of Pimephales promelas and a characterization of effects on freshwater organisms. (English, HTML)

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2018-09-25

Substituted phenylamine antioxidants (SPAs) are used in the production of a variety of consumer products (lubricants, dyes, and polymers). Substituted phenylamine antioxidants (SPAs) increase the life of consumer products by preventing the chain reaction of free radical production initiated by exposure to heat, oxygen, ozone, radiation and stress. It is important to consider that based on their physicochemical properties, substituted phenylamine antioxidants (SPAs) are likely to partition into sediment when they enter an aquatic system. Thus the most likely environmentally relevant pathway for fish to become exposed to SPAs would be through contaminated sediment. This data set investigated the effect of sub chronic exposure in the early life stages of the Fathead minnow (Pimephales promelas) to sediment spiked with substituted phenylamine antioxidants (SPAs). An advantage of testing during the early embryo-larval stages of a fish life is that they tend to be more sensitive to toxicants compared to more mature life stages of fish. Four SPAs were tested in this dataset: Diphenylamine [DPA], N-phenyl-1-napthylamine [PNA], N-(1,3-dimethylbutyl)-N’-phenyl-1,4 phenylenediamine [DPPDA],…

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