Summary Safety Review - Proton Pump Inhibitors - Assessing the Potential Risk of Clostridium difficile Infection (English, HTML)

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Publisher-reported update

2024-05-10

This safety review was carried out to look at new information in the scientific literature that has emerged since the completion of a previous review in 2012 about the risk of Clostridium difficile infection with proton pump inhibitor use. Clostridium difficile infection ranges from mild diarrhea to life-threatening multi-organ failure, especially in elderly patients with other pre-existing conditions.

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